Administration of Potassium via a Peripheral Line

1. The infusion rate should not exceed 10 mEq/hr.

2. For single dose IV replacement, a concentration up to 40 mEq/500ml or 80 mEq/L may be used. Extended therapy should not exceed 60 mEq/L.

3. The maximum dosage should not exceed 240 mEq/24 hr.

4. If the patient has compromised cardiac function or a potassium level lower than 3 mEq/L, cardiac monitoring is advisable.

Administration of Potassium via a Central Line

1. When higher concentrations are required, 10 –20 mEq of potassium may be mixed in 100 ml of fluid and infused over 1 hour. This may be repeated if necessary.

2. In a critical care setting, up to 30 mEq/hr may be administered with a minimum dilution of 10mEq/25ml.

3. Concentrations greater than 30 mEq/hr may only be administered in the critical care setting when the patient is on a cardiac monitor and the prescribing physician is in attendance.

Monitor:

1. Serum potassium – initial and follow-up

2. Urine output

3. Pain at injection site

4. Cardiac monitoring for infusion rates in excess of 10 mEq/hr

5. Infusion pump must be used if rate exceeds 10 mEq/hr or for concentrations greater than 40 mEq/l.