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Insulin Comparison Chart

 

 

Onset

Peak

Duration

Appearance

RAPID ACTING

Apidra (glulisine)

20 min

45 min to 1 hour

5 to 6 hours

clear

Humalog (lispro)

15 to 30 min

30 min to 1.5 hours

3 to 5 hours

clear

Novolog (aspart)

10 to 30 min

1 to 3 hours

3 to 5 hours

clear

SHORT ACTING

Novolin Regular (R)

30 min to 1 hour

1 to 5 hours

3 to 10 hours

clear

Humulin Regular (R)

30 min to 1 hour

1 to 5 hours

3 to 10 hours

clear

INTERMEDIATE ACTING

Novolin NPH (N)

1 to 4 hours

4 to 14 hours

10 to 24 hours

cloudy

Humulin NPH (N)

1 to 4 hours

4 to 14 hours

10 to 24 hours

cloudy

Novolin Lente (L)†

1 to 4 hours

4 to 14 hours

12 to 24 hours

cloudy

Humulin Lente (L)†

1 to 4 hours

4 to 14 hours

12 to 24 hours

cloudy

LONG ACTING

Humulin Ultra Lente (U)†

4 to 10 hours

8 to 30 hours

18 to 36 hours

cloudy

Lantus (glargine)

1 to 2 hours

peakless

20 to 24 hour basal insulin

clear

INTERMEDIATE ACTING + SHORT ACTING

Humulin 70/30 mix

30 min

2 to 12 hours

24+ hours

cloudy

Humulin 50/50 mix

approx. 30 min to 1 hour

approx. 2 to 12 hours

18 to 24 hours

cloudy

INTERMEDIATE-ACTING + RAPID-ACTING

Novolog 70/30 mix

approx. 10 to 30 min

approx. 1 to 3 hours

up to 24 hours

cloudy

Humalog 75/25 mix

approx. 15 to 30 min

approx. 1 to 3 hours

16 to 20 hours

cloudy

† Product no longer marketed in United States

·            Onset, peak, and duration may vary considerably from person to person

·            When mixing insulin in a syringe, ALWAYS draw up the quickest acting insulin first

·            Only HUMULIN R may be infused intravenously

·            NEVER mix Lantus with other insulins

 

**NOTE: There is not sufficient data available for the onset, peak, and duration of the following products:  Humulin 50/50, Novolog 70/30, and Humalog 75/25.  Values listed above are APPROXIMATED values.



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