Department
Pharmaceutical Sciences
Office
Research & Graduate Studies
Education and Training
- 2024 – Now Ph.D. of Interdisciplinary Biomedical Sciences (GPIBS) | Pharmacology, Toxicology, and Experimental Therapeutics (PTET), Department of Pharmacology and Toxicology, Faculty of Medicine, University of Arkansas for Medical Sciences (UAMS), Little Rock, Arkansas, USA.
- 2023 – 2024 Master Research in Drug Design and Development, Department of Pharmacology, Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. Thesis title “Design and development of PROTACs and AUTACs as potential Inhibitor for ferroptosis”.
- 2020 – 2023 Master of Pharmacology, Department of Pharmacology and Toxicology, Faculty of Medicine and Graduate Studies, An-Najah National University, Nablus, Palestine. Thesis title ‘Down-regulation of beta-catenin by siRNA complexed with carbon nanotube’.
- 2015 – 2020 Bachelor of Pharmacy, Department of Pharmacy, Faculty of Medicine and Health, An-Najah National University, Nablus, Palestine. Thesis title ‘Triple functionalization of single walled nanotubes with Doxorubicin, mannose and fluorescent for cancer therapy.
Teaching Responsibilities
- Pharmacology and Toxicology
- Cell Biology and Chemical Biology
- Medicinal Chemistry
- Drug Design and Development
Clinical Practice
Pharmacist with expertise in clinical pharmacology and Toxicology, providing medication therapy management, patient counseling, and drug utilization review. Experienced in community pharmacy practice and clinical consultations aimed at optimizing pharmacotherapy and improving patient outcomes.
Mission Areas
Advancing drug design and development, drug discovery, and protein degradation research (including PROTACs, AUTACs, and SNIPER technology). Committed to pioneering chemical biology and cancer biology research, with a focus on pharmacology, toxicology, and medicinal chemistry. Dedicated to enhancing therapeutic innovation and promoting evidence-based medication safety and efficacy.
Research and Scholarly Interests
Drug Design and Development, Drug Discovery, Protein Degradation platforms (PROTACs, AUTACs, SNIPER, etc), Chemical Biology, Cancer Biology, Pharmacology, Toxicology, and Medicinal Chemistry.
Publications
- Ghareeb, A., Ghazal, N., Assali, M., Kittana, N., Khader, A. and Daraghmeh, M., 2025. Novel siRNA Delivery System Targeting β-Catenin in Colorectal Cancer Cells: Synergistic effect with 5-Fluorouracil. Journal of Drug Delivery Science and Technology, p.107082.
- Sawalha, S., Abdallah, S., Barham, A., Badawi, H., Barham, Z., Ghareeb, A.,Misia, G., Collavini, S., Silvestri, A., Prato, M. and Assali, M., 2023. Green synthesis of fluorescent carbon nanodots from sage leaves for selective anticancer activity on 2D liver cancer cells and 3D multicellular tumor spheroids. Nanoscale Advances, 5(21), pp.5974-5982.
- Abu-Jabal, S., Ghareeb, A., Smadi, D., Hamed, O., Assali, M., Berisha, A., Abutaha, N., Mansour, W., Omairah, A., Janem, A. and Jaser, A., 2023. New Zwitterionic Imidazolones with Enhanced Water Solubility and Bioavailability: Synthesis, Anticancer Activity, and Molecular Docking. Chemistry, 5(4), pp.2613-2629.
- Ghareeb, A., Down-regulation of beta-catenin in cancer cells by siRNA complexed with carbon nanotube. 2022, An-Najah National University: Nablus, Palestine.
- Ghareeb, A., Khader, A., Daragmeh, .M, Triple functionalization of single walled nanotubes for cancer therapy. 2020, An-Najah National University: Nablus, Palestine..