TRI Names Four Implementation Science Pilot Awardees

The UAMS Translational Research Institute (TRI) has approved research pilot study awards for four researchers totaling $200,000.

The annual awards of up to $50,000 each are made to projects with the strongest likelihood of leading to improved health and health care. This is the first year TRI has offered awards for pilots focused on implementation science projects.

Implementation science is the study of methods to promote the systematic uptake of research findings and other evidence-based practices into routine practice to improve the quality and effectiveness of health services.

Awardees were selected using a Study Section modeled after an NIH review panel, with internal, external and community reviewers. The awardees are:

Pearl McElfish, Ph.D., MBA, Associate Vice Chancellor, Northwest Arkansas Campus, Director of the Office of Community Health and Research, Co-Director of the Center for Pacific Islander Health, Assistant Professor, Internal Medicine
Pilot project: Implementation of Family Model DSME in an Underserved Marshallese Population in a Clinical Setting

Benjamin Teeter, Ph.D., Assistant Professor, Pharmacy Practice, Center for Implementation Research
Pilot project: Testing Implementation Strategies to Support Community Pharmacist-Initiated Prescription and Distribution of Naloxone to Reduce Overdose by Opioids

Jeremy Thomas, Pharm.D., Associate Professor, Department of Pharmacy Practice
Pilot project: Implementation of Clinical Pharmacy Services Delivered via Telehealth to Federally Qualified Healthcare Centers

Kristin Zorn, M.D., Associate Professor, Gynecology Oncology and Genetics
Pilot project: An Implementation Strategy to Increase Appropriate Referrals for Genetic Counseling and Testing Among Patients at High Risk for Hereditary Cancer Syndromes

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Pharmaceutical Sciences Department Seeks Applications for Tenure Track Positions

The University of Arkansas for Medical Sciences (UAMS) College of Pharmacy seeks applications for two tenure track positions in the Department of Pharmaceutical Sciences at any academic rank, commensurate with background and experience.

The Department of Pharmaceutical Sciences has approximately 30 full-time faculty members, 10 research faculty, 25 post docs and research staff, and 20 graduate students, and is in a state of rapid growth and advancement. Candidates should have research credentials in the general area of Drug Discovery and Development, and should have experience in one or more of the following areas: medicinal chemistry, pharmacology, pharmaceutics, radiation health or computational science. Preferred areas of interest include, but are not limited to, cancer, radioprotection, neuropathology, and cardiovascular disease. Responsibilities will also include a commitment to innovative teaching and mentoring at the professional, graduate and postdoctoral level. The Department maintains a strong commitment to professional education by delivering approximately half of the didactic professional curriculum and has an active graduate program in Pharmaceutical Sciences.

The positions are full-time, 12-month appointments. Applicants must possess a terminal degree in pharmacy, chemistry, pharmacology, toxicology, biochemistry or other related fields, have excellent communication and interpersonal skills, have established an independent research program, and demonstrated leadership through national recognition in their research area. Externally funding is preferred but not an absolute requirements. The ideal candidate should possess a working knowledge of academic pharmacy. Collaborative research opportunities for faculty members exist within several prominent research centers at the University of Arkansas for Medical Sciences, including the Rockefeller Cancer Institute, the Myeloma Institute, the Translational Research Institute, the Stephens Spine and Neurosciences Institute and the Reynolds Center for Aging. Research is also supported by various research and service centers/cores, including Biomedical Mass Spectroscopy, Cyclotron and Radiochemistry labs, Magnetic Resonance and PET Imaging and Spectroscopy, the Biostatistics Consulting Unit, and the Department of Lab Animal Medicine. Excellent opportunities also exist for entrepreneurial activities in the nearby Bioventures campus incubator facility.

Salary will be competitive and commensurate with education and experience, and a generous start-up package will be available. Candidates for this position must be able to meet eligibility requirements for work in the United States at the time the appointment begins and be able to communicate effectively in English.

UAMS is an academic health science campus located in Little Rock that consists of six academic units. As one of the largest public employers in the state, UAMS employs approximately 10,500. The campus consists of six institutes, University Hospital, the Central Arkansas Veterans Administration Medical Center, eight Area Health Education Centers around the state, and Arkansas Children’s Hospital. The College of Pharmacy has approximately 70 full-time faculty members, 400 volunteer faculty, and 480 Pharm.D. students.

Little Rock, Arkansas offers a unique professional and living environment and is located approximately 120 miles west of Memphis, Tennessee, 250 miles northeast of Dallas, Texas, and 350 miles south of St. Louis, Missouri. The Little Rock – North Little Rock communities consist of approximately 500,000 people and offer a high quality of life with a modest cost of living, excellent schools, and recreational opportunities.

To assure full consideration, applications must include curriculum vitae, letter of interest providing a summary of qualifications for the position, and three letters of reference. Applications will be sought until the position is filled. Applications and nominations should be submitted to Dr. Peter A. Crooks, Chairman, Department of Pharmaceutical Sciences, UAMS College of Pharmacy, 4301 West Markham Street, #522, Little Rock, Arkansas 72205. Applicants may contact Dr. Crooks at PACrooks@uams.edu or 501- 686-6495.

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UAMS Center for Implementation Research Featured in First of Its Kind Special Issue

Research in Social and Administrative Pharmacy has released its “Special Issue on Implementation Science.” Co-edited by Dr. Geoffrey Curran, UAMS College of Pharmacy Director of Center for Implementation Research and Professor, the special issue features multiple faculty authors. This special issue is dated September-October 2017, volume 13, issue 5.

College of Pharmacy Class of 2021 Dons White Coats

On a recent trip, Grazyna Nowak, Ph.D., was reluctant to switch rooms when the hotel management asked if she would, she said Aug. 18 at the  White Coat Ceremony for the UAMS College of Pharmacy Class of 2021.

A professor in the college’s Department of Pharmaceutical Sciences and a recipient of the 2017 Pharmaceutical Sciences Outstanding Faculty Award, Nowak was the keynote speaker at the ceremony.

“I was happy with my room, enjoyed the surroundings, and appreciated the company of friendly birds that visited my balcony to ask for treats,” she said.

Despite her misgivings, Nowak decided to take a chance and embrace the possibility the room might be even better than her first one.

She started to regret her choice when she found the pathway to the new room was dull and also required passing by a noisy maintenance facility. Regret faded fast however when she opened the door.

“Across from me was a view I will never forget,” Nowak said. “It was a view of beautiful lush green mountains and tall waterfalls cascading down vertical cliffs; a view of nature free of any signatures of civilization, a view almost too perfect to be real.”

Because often we don’t like change and are uncomfortable with the unknown, we hesitate to recognize and seize opportunities, she said.

“Life presents you an opportunity now — one offered only to those who have been persistent and motivated, who have worked hard to learn a lot, who have the qualities necessary to become a health care professional,” Nowak said to the first-year students.

She said four years ago, the profession of pharmacist was ranked the third best profession in the nation based on 10-year growth volume, median salary, employment rate, future job prospects, opportunities for training and advancement, stress level and work-life balance.

Pharmacy isn’t limited to the retail environment, Nowak explained. Although rewards are there, too, pharmacy graduates have a diversity of other career paths from which to choose, including chemotherapy pharmacy, nuclear pharmacy, drug development, long-term care and education.

After Nowak spoke, the 123 students in the Class of 2021 one by one walked on stage to put on white coats to mark symbolically the beginning of their four years of study and their transition into the life of a student-pharmacist.

“Your white coat stands out because it is important to your patient care, it is a sign of caring, a sign of compassion for your patients,” College of Pharmacy Dean Keith Olsen, Pharm. D., said. “By donning the white coat, your patients expect the utmost professionalism from each of us. They expect the best every day. I have no doubt each of you will thrive in your white coat and in the College of Pharmacy.”

Sponsored by the Arkansas Pharmacists Association (APA), it was the college’s 15th annual White Coat Ceremony. Representing the APA at the ceremony was Scott Pace, Pharm. D., the association’s executive vice president and CEO.

About 600 people attended, including college faculty and staff, and friends and family.

Following the keynote address, Meghan Petersen, president of the UAMS American Pharmacists Association-Academy of Student Pharmacists UAMS Chapter, led the Class of 2021 in reciting the Student Pledge of Professionalism.

The average grade point average of the incoming class, which includes 49 males and 74 females, was 3.46.

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UAMS Study Finds Day-Supply of Prescribed Opioids Most Decisive Factor in Likelihood of Long-Term Use

The single biggest factor determining whether a patient is likely to use opioids long term may be the number of days’ supply initially prescribed, according to a study by UAMS researchers.

“Compared to someone prescribed two days versus seven days, that person with a seven-day supply is twice as likely to be using opioids in the long term,” said Bradley Martin, Pharm.D., Ph.D. “The days supplied is far more important than the dosage level or even the type of pain being treated.”

The study was published online this month in The Journal of Pain by Martin and UAMS researchers Anuj Shah, a Ph.D. student, and Corey Hayes, Pharm.D., a postdoctoral fellow.

They looked at people previously prescribed opioids who had not used one in six months, the number of days on an opioid prescription they initially received, and whether they were still using opioids one year later.

Their most recent study is a follow-up to an earlier study by Martin, Shah and Hayes published in March in the Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report that more broadly examined the effect of the day-supply of opioids on long-term use.

The study used 1.3 million patient records from 2006-2015 that were drawn from the IMS Lifelink+ database, which includes commercial health plan information and de-identified information on the enrollees.

In the follow-up study, Martin, Shah and Hayes examined the likelihood of long-term use of opioids among patients who received opioids for chronic pain, surgery, trauma and other pain conditions.

“In our previous study, we looked at anyone who was prescribed an opioid for any reason,” Martin said. “Now, people with chronic pain compared to people who just had surgery are about 25 percent more likely to continue using opioids. Clearly, people with chronic pain are more likely to be long-term opioid users. The type of pain does matter, but before doing the study we thought chronic pain versus surgical pain would be a stronger predictor of long-term use.”

Martin, the senior author of the study, is a professor in the Division of Pharmaceutical Evaluation and Policy in the UAMS College of Pharmacy’s Department of Pharmacy Practice. Shah, a co-author with Martin and Hayes, is a Ph.D. student in the division and a fellow at the Arkansas Center for Health Improvement, and Hayes is a postdoctoral fellow in the UAMS College of Medicine’s Department of Psychiatry.

The vast majority of people with an initial episode of opioid use discontinue opioids, the study showed. On average, more than 80 percent of chronic pain patients discontinue in less than a year, and 90 percent with non-chronic pain discontinue in less than a year.

While there is no clear and specific point of transition to chronic use, the longer the duration an initial opioid prescription lasts the higher the chances opioid use will continue months or even years later, according to the study.

“Comparing someone who has a one- or two-day supply of opioids with someone who has a week’s supply the risk of use doubles,” Martin said. “This is something clinicians can easily modify when they prescribe opioids.”

Data obtained for this project was supported by the UAMS Translational Research Institute (TRI), grant UL1TR000039. Dr. Hayes was supported by the Translational Training in Addiction [1T32 DA 022981].

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UAMS Student Pharmacists Win Historic Four-Award Sweep in National Competition

For the first time in the history of the American Pharmacists Association (APhA) student awards competition, students of the UAMS College of Pharmacy took home all four national awards for patient care and education.

They garnered the historic win March 27 in San Francisco during the APhA annual meeting.

About 300 students of the UAMS College of Pharmacy are members of the APhA-Academy of Student Pharmacists chapter that took home the awards, which were given to the chapter in recognition of its achievements in patient care and education for diabetes, cardiovascular health, over-the-counter (OTC) medicine safety and immunization.

“I think UAMS pharmacy students are the best in the country and this just proves, it in my opinion,” said Eddie Dunn, Pharm.D., the chapter’s faculty advisor. “It’s especially good to know that a national association of professional pharmacists sees it, too, and shares that high opinion. These students worked especially hard to earn this recognition. The entire college is proud of them.”

Dunn is an associate professor in the College of Pharmacy’s Department of Pharmacy Practice.

Operation Heart is a national, public education project of APhA-ASP, and Operation Diabetes seeks to identify individuals with previously undiagnosed diabetes while increasing overall awareness of the disease. Operation Immunization is an immunization education campaign that also works to raise the number of adults receiving immunizations.

OTC Medicine Safety is a campaign of APhA-ASP Chapters to educate fifth- and sixth-graders in reading medicine directions, following those directions, proper measuring of medicine, safe storage and disposal of medicine and consulting with parents or guardians before taking medications.

To win all four awards, the students throughout the 2015-2016 academic year participated in dozens of public outreach events as well as organized many of their own and visited public schools, Dunn said.

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