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College of Pharmacy

Amit K. Tiwari Ph.D., DABT

Amit K. Tiwari Ph.D., DABT
Associate Dean of Research and Graduate Studies; Professor of Pharmaceutical Sciences
Location: Biomedical Bldg II, Rm 140-2E
Phone: 501-526-7388
Fax: 501-686-6057
Email: atiwari@uams.edu
 

Pharmaceutical Sciences

Education and Training

  • Postdoc, Mount Sinai School of Medicine, NY, 2013
  • Ph.D., Pharmaceutical Sciences, St. John’s University, NY, 2011
  • M.S., Pharmaceutical Sciences, St. John’s University, NY, 2008
  • B.S., Pharmacy RamEesh Institute, U.P.T.U., India, 2005

Research and Scholarly Interests

  • Dr. Tiwari directs the Cancer and Systems Therapeutics (CAST) program at the University of Arkansas for Medical Sciences. CAST team is involved in a) developing effective, safe, and targeted anticancer therapeutics against multidrug-resistant cancers; b) designing, synthesizing and characterizing non-conventional forms of cell death inducers i.e. modulators of necroptosis, methuosis, and autophagy. CAST is also engaged in innovative drug delivery systems, natural products drug discovery, and chemical toxicity. CASTers are particularly interested in the identification of novel targets (single and multi-targets), synthesis and optimization of lead compounds, PK (ADME), PD (i.e. efficacy, model/assay developments, and mechanistic studies), drug-drug/herbal interactions, drug resistance, advanced toxicology assessments, and IP protection and commercialization.

Honors and Awards

SELECTED

  • Ambassador Award, Awarded by Govt. of Madhya Pradesh, India, in collaboration with MP Council of Science and Technology, 2023
  • President’s Award for Excellence in Creative and Scholarly Activity, University of Toledo, 2022
  • Outstanding Research and Scholarship Award, University of Toledo, 2022
  • Distinguished Young Alumni Award, St. John’s University, 2022
  • Outstanding Advisor Award, University of Toledo, 2021
  • Distinguished Scientist Award, International Association of Pharmacy Professionals, 2021

Memberships

  • American Association of Pharmaceutical Science
  • American Association of College of Pharmacy
  • American Cancer Society
  • Society of Toxicology
  • American Association for Cancer Research
  • American Society of Pharmacology and Experimental Therapeutics
  • American Association of University Professors
  • The Rho Chi Society
  • The Sigma Phi Sigma Society

Publications

Google Scholar

PUBMED

SELECTED PATENT APPLICATIONS

  • Raman D, Howard C, Nemunitis J, Brunicardi FC, Liu SH, and Tiwari AK. Targeting LASP1, elF4A1, e1F4B and CXCR4 with modulators And Combinations Thereof for Cancer Therapy (provisional D-2019-32, Ser. No. 62/807,075.) 2019
  • Tiwari AK, Hussein N, Ashby CR. Cariprazine and its analogues use in cancer therapy. (Application 60893-US-PSP/D2019-33, No. 62/934,638) 2019
  • Tiwari AK, Karthikeyan C, Nyinawabera, A. Necroptosis inducers and autophagy inhibitors in cancer therapy. (US patent application 2018, 60088-US-PSP/D2018-45).
  • Tiwari AK, Karthikeyan C, Amawi H, Erhardt P and Trivedi P. Materials and Methods Useful to Induce Cancer Cell Death Via Methuosis Or Autophagy Or A Combination Thereof. (US patent application 2017, 59593-US-PSP/D2018-15). Published 08-09-2022 – US11406626B2