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  1. University of Arkansas for Medical Sciences
  2. College of Pharmacy
  3. Research
  4. Core Facilities
  5. Experimental Radiation Core

Experimental Radiation Core

The Experimental Radiation Core maintains and operates equipment and facilities to deliver ionizing radiation for research use. The core can deliver X- and γ-rays at a broad range of dose rates and radiation field sizes for a variety of purposes, such as irradiation of cell cultures, animal whole body irradiation, irradiation of animal tumor models or other (image guided) partial-body irradiation. In addition, the core has two strontium-90 sources for small-field superficial exposures with β-radiation.

Core Services

  • Maintenance of radiation equipment and radiation dosimetry
  • Assistance in design and development of new animal and cell culture radiation models
  • Assistance and training in whole body or localized irradiation of animal models
  • Assistance and training in radiation exposure of cell cultures

Equipment and Facilities

  • Cesium source irradiator that can be used for animal whole body/partial body and cell culture exposures to γ-rays.
  • Cesium source irradiator that can be used for chronic exposure of animals to low-dose rate γ-rays.
  • Seifert Isovolt 320 X-ray generator. This X-ray machine can be used for localized irradiation.
  • Small Animal Radiation Research Platform (SARRP, Xstrahl). This system incorporates cone beam computed tomography (CBCT) imaging and radiation planning software to deliver precise X-ray beams to anatomical targets, similar to clinical radiation therapy.
  • X-Rad 320 (Precision X-Ray). This is an X-ray cabinet for the irradiation of cell cultures and small animals.
  • Strontium-90 β-sources. These sources can be used for irradiation of superficial targets such as skin while minimizing exposure of underlying tissues.

Pricing and Scheduling

  • Cesium source irradiator: $125 per hour (with assistance from core staff)
  • Cesium source irradiator (select trained users who do not need assistance from core staff): $85 per hour
  • SARRP (operated by core staff only): $130 per hour

For scheduling, please contact either of the following:

Nukhet Aykin-Burns
NAykinburns@uams.edu
501-603-1375

Kim Krager
kjkrager@uams.edu

Marjan Boerma
mboerma@uams.edu
501-686-6599

SARRP

This irradiator incorporates CBCT imaging and radiation planning software to deliver precise X-ray beams to anatomical targets. The target can be exposed through a single beam, multiple beams, or arcs, matching clinical radiation therapy techniques.

Chronic irradiation facility

A chronic irradiation facility was built in 2018, using a cesium source that is capable of scattering radiation in all direction at pre-set dose rates. The configuration in the figure will lead to a dose rate of approximately 0.1 cGy/hour. Animals can be housed around the source and irradiated continuously for hours up to several months.

UAMS College of Pharmacy LogoUAMS College of PharmacyUniversity of Arkansas for Medical Sciences
Mailing Address: 4301 West Markham Street, Little Rock, AR 72205
Phone: (501) 686-7000
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