Division of Radiation Health
Department of Pharmaceutical Sciences
UAMS College of Pharmacy
Biomed Building II 401-2
E-mail address: vmohanseenivasan@uams.edu
Phone: 501-686-5531
Fax: 501-686-6057
- Dr. Mohan Seenivasan (Marital Name: Vijayalakshmi Sridharan) received her Ph.D in Biochemistry and Molecular Biology from University of Madras (Chennai, TamilNadu, India) and received post doctoral training at Medical University of South Carolina (MUSC) and University of Arkansas for Medical Sciences (UAMS), USA.
- Dr. Mohan Seenivasan is Research Instructor of Pharmaceutical Sciences at UAMS, and a member of the Division of Radiation Health in the College of Pharmacy.
- Dr. Mohan Seenivasan’s research focuses on the interactions between ionizing radiation and normal tissues, particularly the molecular mechanisms that lead to the development of radiation-induced heart disease and the identification of potential treatments.
Recent Publications
Vijayalakshmi Sridharan, Preeti Tripathi, Sunil K. Sharma, Eduardo G. Moros, Junying Zheng, Martin Hauer-Jensen, Marjan Boerma. Roles of sensory nerves in the regulation of radiation-induced structural and functional changes in the heart. Int J Radiat Oncol Biol Phys 2013; in press
Vijayalakshmi Sridharan, Preeti Tripathi, Sunil K. Sharma, Peter M.Corry, Eduardo G. Moros, Awantika Singh, Ceasar M. Compadre, Martin Hauer-Jensen, Marjan Boerma. Effects of late administration of pentoxifylline and tocotrienols in an image-guided rat model of localized heart irradiation. PLoS One. 2013 Jul 22;8(7):e68762. doi: 10.1371/journal.pone.0068762. Print 2013. http://www.ncbi.nlm.nih.gov/pubmed/23894340
Vijayalakshmi Sridharan, Sunil K. Sharma, Eduardo G. Moros, Peter M. Corry, Preeti Tripathi, Benjamin J. Lieblong, Chandan Guha, Martin Hauer-Jensen, Marjan Boerma. Effects of radiation on the epidermal growth factor receptor pathway in the heart. Int J Radiat Biol. 2013 Jul;89(7):539-47. doi: 10.3109/09553002.2013.782110. Epub 2013 Apr 16 http://www.ncbi.nlm.nih.gov/pubmed/23488537
Vijayalakshmi Sridharan, Preeti Tripathi, Sunil K. Sharma, Eduardo G. Moros, Peter M. Corry, Benjamin J. Lieblong, Elena Kaschina, Thomas Unger, Christa Thöne-Reineke, Martin Hauer-Jensen, Marjan Boerma. Cardiac inflammation after local irradiation is influenced by the kallikrein-kinin system. Cancer Res 2012;72:4984-92 [PMID: 22865451] http://www.ncbi.nlm.nih.gov/pubmed/22865451
Rupak Pathak, Snehalata A. Pawar, Qiang Fu, Prem K. Gupta, Maaike Berbée, Sarita Garg , Vijayalakshmi Sridharan, Wenze Wang , Prabath G. Biju, Kimberly J. Krager , Marjan Boerma, Sanchita P Gosh, Amrita K. Cheema, Howard P. Hendrickson, Nukhet Aykin-Burns, Martin Hauer-Jensen. Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses. Antioxid Redox Signal. 2013 May 3. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/23521531
Marjan Boerma, Junuru Wang, Vijayalakshmi Sridharan, Jean-Marc Herbert, Martin Hauer-Jensen. Pharmacological induction of transforming growth factor-beta1 in rat models enhances radiation injury in the intestine and the heart. PLoS One. 2013 Jul 25;8(7):e70479. doi: 10.1371/journal.pone.0070479. Print 2013
http://www.ncbi.nlm.nih.gov/pubmed/23936211
Sunil K. Sharma, Eduardo G. Moros, Marjan Boerma, Vijayalakshmi Sridharan, Eun Y. Han, Richard Clarkson, Martin Hauer-Jensen, Peter M. Corry. A Novel Technique for Image-Guided Local Heart Irradiation in the Rat. Technol Cancer Res Treat. 2013 Aug 31. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/24000983